Reiße, S., Haack, M., Garbe, D., Sommer, B., Steffler, F., Carsten, J., Bohnen, F., Sieber, V., Brück, T. (2016) In Vitro Bioconversion of Pyruvate to n-Butanol with Minimized Cofactor Utilization Front. Bioeng. Biotechnol., DOI: 10.3389/fbioe.2016.00074

Görner, C., Schrepfer, P., Redai, V., Haslbeck, M., Wallrapp, F., Loll, B., Eisenreich, W., Brück, T. (2016) Identification, characterization and molecular adaptation of class I redox systems for the production of hydroxylated diterpenoids. Microb.Cell.Fac. 15:86, DOI: 10.1186/s12934-016-0487-6

Endres, C., Roth, A., Brück, T. (2016) A thermal reactor model for large-scale algae cultivation in vertical flat panel photobioreactor. Enivr. Sci. Eng. 50(7):3920-7, DOI: 10.1021/acs.est.5b05414



Schrepfer, P., Görner, C., Redai, V., Büttner, A., Hertel, M., Wallrapp, F., Eisenreich, W., Sieber, V., Kourist, R., Brück, T. (2015) Identification of amino acid networks governing catalysis in the closed complex of class I terpene synthases. P.N.A.S. doi: 10.1073/pnas.1519680113

Glemser, M., Heining, M., Schmidt, J., Becker, A., Buchholz, R., Brück, T. (2015) Application of light-emitting diodes (LEDs) in cultivation of phototrophic microalgae: current state and perspectives. Appl.Microb.Biotech. 12, 1-12 (doi: 10.1007/s00253-015-7144-6).

Görner, C., Redai, V., Bracharz, F., Schrepfer, P., Garbe, D., Brück, T. (2015) Genetic engineering and production of modified fatty acids by the non-conventional oleaginous yeast Trichosporon oleaginosus ATCC 20509. Green Chem. (doi: 10.1039/c5gc01767j)

Kourist, R., Bracharz, F., Lorenzen, J., Kracht, O.N., Chovatia, M., Daum, C., Deshpande, S., Lipzen, A., Nolan, M., Ohm, R.A., Grigoriev, I.V., Sun, S., Heitman, J., Brück, T and Nowrousian, M. (2015) Genomics and Transcriptomics Analyses of the Oil-Accumulating Basidiomycete Yeast Trichosporon oleaginosus: Insights into Substrate Utilization and Alternative Evolutionary Trajectories of Fungal Mating Systems. mBio 6(4), e00918-15. (doi: 10.1128/mBio.00918-15)

Görner, C., Hirte, M., Huber, S., Schrepfer, P., Brück, T. (2015) Stereoselective chemo-enzymatic oxidation routes for (1R,3E,7E,11S,12S)-3,7,18-dolabellatriene. Front. Microbiol. 6, 1115. (doi: 10.3389/fmicb.2015.01115)

Heilmann, M., Jurkowski, W., Buchholz, R., Brueck, T., Becker, A.M., (2015) Biosorption of Neodymium by Selected Photoautotrophic and Heterotrophic Species. J. Chem. Eng. Process Technol. 6, 4 (

Brück, W.M., Bracharz, F., Brück, D.W., Brück, T.B., (2015) Mikrobiologische Nutzung von Fischerei-Abfall: Von der Krebsschale in die Creme. Biologie unserer Zeit. 3 (45), 160-167 (doi:10.1002/ biuz.201510561)

Qoura, F., Kassab, E., Reiße, S., Antranikian, G, Brück, T. (2015) Characterization of a thermo-active subtilisin-like serine protease from the psychrophilic bacterium Shewanella arctica. J. Mol.Cat. B, Enzymatic. 116, 16–23

Reiße, S., Garbe, D., Brück, T. (2015) Identification and optimization of a novel thermo- and solvent stable ketol-acid reductoisomerase for cell free isobutanol biosynthesis. Biochimie 108, 76-84

Sommer, B., von Moeller, H., Haack, M., Qoura, F., Langner, C., Bourenkov, G., Garbe, D., Loll, B., Brück, T. (2015) Detailed structure-function correlations of Bacillus subtilis Acetolactate Synthase. ChemBioChem 16 (1), 110-18

Brück, W., Bracharz, F., Brück, D. W. and Brück, T. B. (2015), Von der Krebsschale in die Creme. Biologie in unserer Zeit, 45: 160–167. doi: 10.1002/biuz.201510561

Reiße, S., Garbe, D., Brück, T. (2015) Identification and optimization of a novel thermo- and solvent stable ketol-acid reductoisomerase for cell free isobutanol biosynthesis. Biochimie 108, 76-84

Qoura, F., Kassab, E., Reiße, S., Antranikian, G, Brueck, T. (2014) Characterization of a thermo-active subtilisin-like serine protease from the psychrophilic bacterium Shewanella arctica. Journal of Molecular Catalysis. B, Enzymatic.


Brück WM, Gibson G, Brück TB. The effect of proteolysis on the induction of cell death by monomeric alpha-lactalbumin (2014) Biochimie 97, 138-143

Brück, T.B., Kourist, R., Loll, B. (2014) Production of macrocyclic sesqui- and diterpenes in heterologous microbial hosts: A systems approach to harness nature's molecular diversity ChemCatChem 6 (5), 1142–1165

Janke, R., Görner, C., Hirte, M., Brück, T.B., Loll, B. (2014) Crystal structure of the first bacterial diterpene cyclase: CotB2. Acta Cryst. D 70, 1528-1537

Reiße, S., Garbe, D., Brück, T. (2014) Meiothermus ruber thiolase - a new process stable enzyme for improved butanol synthesis. Biochimie 103, 16-22

Qoura, F., Brück, T., Antranikian, G. (2014) The psychrophile Shewanella arctica sp. nov.: a new source of industrially important enzyme systems. JSM Biotechnology and Biomedical Engineering 2 (1), 1026-35

Garbe, D., Reiße, S., Brück, T. (2014) Biomasse-basierte Lipide: Nachhaltige Bausteine für die Kunststoff-Herstellung. Chemie in unserer Zeit 48 (4), 284-95

Qoura, F., Elleuche, S., Brück, T., Antranikian, G. (2014) Purification and characterization of a cold-adapted pullulanase from a psychrophilic bacterial isolate. Extremophiles 18, 1095-102


Bohnen F, Brück TB. A critical review of algae process optimization using design of experiment methodologies (2013) JSM Biotechnol.Bioeng. 1(3), 1015

Sommer B, Garbe D, Brück TB. Catalytic modules in non-natural butanol biosynthesis: Conversion of the key intermediate crotylalcohol to n-butanol via a designed enzyme cascade, (2013) JSM Biotechnol.Bioeng. 1(2), 1010

Sommer B, Garbe D, Schrepfer P, Brück T. Characterization of a highly thermostable 
ß-hydroxybutyryl CoA dehydrogenase from Clostridium acetobutylicum ATCC 824, (2013) Journal of Molecular Catalysis. B, Enzymatic Volume 98, pp. 138–144

Brück TB, Bohnen F. The Biodiesel Dilemma: A techno- and socioeconomic review of EU legislative actions, (2013) JSM Biotechnol.Bioeng. 1(2), 1009

Görner C, Häuslein I, Schrepfer P, Eisenreich W, Brück TB. Targeted engineering of cyclooctat-9-en-7-ol synthase: A stereospecific access to two new, non-natural fusicoccane-type diterpenes, (2013) Chem.Cat.Chem.  5, pp. 3289–3298

Zhao C, Brück TB, Lercher JA. Catalytic deoxygenation of microalgae oil to green hydrocarbons, (2013) Green Chem 15, 1720-1739

Bis 2012

Guterl JK, Garbe D, Carsten J, Steffler F, Sommer B, Reiße S, Philipp A, Haack M, Rühmann B, Koltermann A, Kettling U, Brück T, Sieber V. Cell-free metabolic engineering: production of chemicals by minimized reaction cascades. (2012) Chem Sus Chem 5, pp. 2165-72

Brück TB, Brück DW. Oxidative metabolism of the anti-cancer agent mitoxantrone by horseradish, lacto-and lignin peroxidase.(2011) Biochimie 93, pp. 217-26

Brück WM, Brück TB, Self WT, Reed JK, Nitecki SS, McCarthy PJ. Comparison of the anaerobic microbiota of deep water Geodia sp. and sandy sediments in the Florida straits, (2010) ISME J 4, pp. 686-699 

Ranzer L, Brueck TB, Lopez J, Kerr RG. A new prokaryotic farnesyldiphosphate synthase from the octocoral Eunicea fusca: differential display, inverse PCR, cloning, and characterization, (2009) Mar Biotechnol (NY) 11(1), pp. 62-73

Al-Ghoul M, Brück TB, Lauer-Fields JL, Asirvatham VS, Zapata C, Kerr RG, Fields GB. Comparative proteomic analysis of matched primary and metastatic melanoma cell lines, (2008) J  Proteome Res  7(9), pp. 4107-18

Santiago LZ, Brück TB, Brück WB, Kerr RG. The diversity of the bacterial communities associated with the azooxanthellate hexacoral Cirrhipathes leutkeni, (2007) ISME J  1, pp. 654-659

Brück TB, Brück WM, Santiago-Vasquez LZ, McCarthy P, Kerr RG. Diversity of the bacterial communities associated with the azooxanthellate deep water octocorallia Leptogorgia minimata, Iciligorgia schrammi and Swiftia exertia, (2007) Mar Biotech 9, pp. 1-1

Brück TB, Kerr RG. Purification and kinetic properties of elisabethatriene synthase from the coral Pseudopterogorgia elisabethae, (2006). Comp Biochem Physiol B 143, pp. 295-302

Brück TB, Harvey PJ. Proteomics: advances, challenges and frontiers, (2005) The Biomedical Scientist 6, pp. 554-564

Brück TB, Harvey PJ. Oxidation of mitoxantrone by lactoperoxidase (2003) Biochim Biophys Acta 1649, pp. 154-163

Brück TB, Gerini MF, Baciocchi E, Harvey PJ. Oxidation of thioanisole and p-methoxythioanisole by lignin peroxidase: kinetic evidence of a direct reaction between Compound II and a radical cation, (2003) Biochem J 374, pp. 761-766

Brück TB, Harvey PJ. Spectrophotometric investigations with hexa-coordinate ferric lignin peroxidase, (2002) Biochem Biophys. Res. Comm. 297, pp. 406-411

Brück TB, Fielding RJ, Symons MCR, Harvey PJ. Mechanism of nitrite stimulated catalysis by lactoperoxidase, (2001) Eur J Biochem. 268, pp. 3214-3222

Brueck TB, Simpson D, Hoban P, Clayton RN, Farrell WC. Amplification of the Cyclin D1 gene in primary pituitary tumours, (1997) J Endocrinol  155, pp. 20-21



  • Brück WM, Reiße S, Garbe G, Brück TB. Industry potential of marine bioactive compounds: Downstream Processing and Vehicles for efficient delivery, (2011) in Marine Bioactive Compounds Sources, Characterisation and applications ed. Hayes M. Springer
  • Brück TB, Garbe G. Algae symbiosis with eukayotic partners, (2012) in Microalgal Biotechnology: Potential and Production ed. Posten C., Walter C. De Gryter



  • WP 309297 Sustainable supply of bioactive marine products. RG Kerr, TB Brück
  • WO/2008/113585 Generation of chemical building blocks from plant biomass by selective hydrolysis. A Koltermann, M Rarbach, TB Brück, U Kettling
  • EP09161030.3. Liquified biomass. A Koltermann, TB Brück, M Rarbach, U Kettling, Z Dragovic, A Kohl, I Bessler, J Gerlach
  • EP09180210 Thermostable xylanases for the selective hydrolysis of pentose-containing polysaccharides. TB Brück, I Beßler, M Rarbach, C Reisinger, A Koltermann, A Kohl, U Kettling, G Hreggvidsson, D Fridjonsson
  • EP10153355.2 Optimized Cellulase Enzymes. TB Brück, C Reisinger, M Rarbach, J Gerlach, I Beßler, J-C Pieck, A Koltermann, L Röcher, D Schlosser, A Kohl, U Kettling, J Claren
  • WO2012139743 Environment friendly method for the production of cement. TB Brück, FM Bohnen, R Sood
  • EP12181085.7 Cell-free and minimized metabolic reaction cascades for the production of chemicals. T Brück, D Garbe, J-K Guterl, V Sieber, M Kraus, M Zavrel, U Kettling
  • WO/2012/089844 Efficient lignocellulose hydrolysis with integrated enzyme production Brück, Thomas; Rarbach, Markus;  Dragovic, Zdravko;  Kohl, Andreas; Gerlach, Jochen; Bartuch, Jörg

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